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Meanwhile, use in more common neurological conditionssuch as migraine and Parkinsons diseasehas been driven largely by empirical efficacy and mechanistic inference, with standardized outcome metrics and controlled trials still lacking ( Importantly, patient responses to riboflavin vary significantly across diseases, indicative of mechanistic specificity underpinning therapeutic benefit

Neurosci Lett 706:158163 Dettmer U, Selkoe D, Bartels T (2016) New insights into cellular -synuclein homeostasis in health and disease

Lewy bodies in grafted neurons in subjects with Parkinsons disease suggest host-to-graft disease propagation

Antioxidants protect the cells against free radicals, unstable molecules the body produces in reaction to various environmental pressures