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Synthetic AT may be divided into two main categories: (i) those that have been primarily developed and synthetized as AT and (ii) compounds that primarily act via different mechanisms of action, while their AT properties were discovered later, which may contribute to their biological activity (as observed for some clinically used drugs, e.g., 4-aminosalicylic acid with inflammatory bowel disease (IBD))

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Key Concepts and Summary The physical properties of a substance depend on the IMFs that the substance experiences

3b) still form an ADPP i state, pointing to slow product release but intact ATP hydrolysis

research is supported by funding from ZJU 100 Young Professor Project, Rut and Arvid Wolff Memorial Foundation (2023-02467), ke Wiberg Foundation (M19-0266), Fredrik and Ingrid Thuring Foundation (2019-00488)