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Weight loss was still accelerating at 48 weeks, suggesting greater reductions may be possible with longer treatment

The company describes retatrutide as an investigational once-weekly triple-hormone receptor agonist that activates GIP, GLP-1, and glucagon receptors with a single molecule.[4] This development history is important because retatrutide was designed as a next-generation incretin therapy rather than as a simple modification of an existing GLP-1 agent

Understand the realistic timeline for results

[17] [18] Supply constraints have affected NHS availability

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