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Quickstart Highlights Tirzepatide is a dual GLP-1/GIP receptor agonist it engages two incretin pathways to curb appetite and improve glycemic control [1] and has been studied for substantial weight loss and broad metabolic improvement in obesity and type 2 diabetes [2] [3]

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This is sometimes referred to as functional hypothalamic amenorrhoea, which can occur with rapid weight loss or significant energy deficits