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132, Oct

302,560 Interestingly, these spatial differences in proliferative capacity are independent of conventional PPAR-mediated fatty acid metabolism

PI3K/AKT signalling, primarily activated by insulin, is crucial for metabolic homeostasis, regulating energy storage and lipid synthesis and breakdown, as well as controlling glucose uptake into adipocytes and other insulin-sensitive tissues, including the promotion of adipogenesis and adipocyte differentiation [56, 57]

[DOI] [PubMed] [Google Scholar] 41.Perkins SE, Yan LL, Shen Z

This activation supports anabolic signaling and protein synthesis in experimental models