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So those are all reasons I see a kind of decline after stenting, if they had been feeling well and then things start going another way
Estrogens and the circadian system
Similarly, conditional knockout mice lacking Cacna1c in the cerebral cortex, which encodes the L-type, voltage-dependent, Ca 2+ -channel, alpha 1 C subunit that is among the most commonly identified risk genes for bipolar disorder, have reduced spontaneous cortical Ca 2+ activity and display hyperactive, manic-like behaviour [27, 28]
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