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Lai JC, Cooper AJ (1986) Brain alpha-ketoglutarate dehydrogenase complex: kinetic properties, regional distribution, and effects of inhibitors
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Intriguingly, there appears to be data of a cumulative action after two or three presentations to the compound, with possibly elevated levels of both growth hormone and IGF-I above baseline on day 14 in many laboratory subjects
Initial treatment may involve daily injections, followed by a weekly or monthly maintenance schedule based on patient response