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Children with genetic conditions like methylmalonic acidemia need careful vitamin B12 management

Nevertheless, use of metformin may decrease vitamin B 12 status: a meta-analysis of four short-term intervention trials (up to 4 months duration) in patients with type 2 diabetes found that metformin use decreased serum cobalamin concentrations by 57 pmol/L, which could have clinical implications if such patients have suboptimal vitamin B 12 status (146)

In these cases, B12 injections are crucial for maintaining adequate nutrition and preventing deficiencies that could arise from altered digestive capabilities

B12 injections help the body produce healthy red blood cells, improving overall vitality and reducing feelings of fatigue