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Furthermore, butyrate treatment did not influence the UCP-1 expression in BAT of vagotomised mice (122), which indicates that the sympathetic nervous system was necessary for butyrate-induced BAT activation

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The cells are protected from the free radicals that may result in damage to cells

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Additionally, hydrogels can be designed for stimuli-responsive drug release, including pH or temperature-sensitive variants, to deliver curcumin under specified physiological conditions (Mahdian et al., 2023)