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Hormonal status: Perimenopausal and postmenopausal women may see a slower response due to estrogen-driven collagen decline

Sermorelin requires intact pituitary function to be effective

Biochemical Pharmacology 147:141-152

By using Tesamorelin, glucose parameters 2 aren't the best early on, but at 6 months, there are no clinically meaningful changes in fasting glucose or 2-hour glucose levels vs a placebo

For compounding pharmacies like Empower, telehealth giant Hims & Hers and a slew of others, which can concoct drugs specifically for individual patients, that puts a potential multi-billion-dollar market within reach