Theoretical concerns similar to all GH-elevating interventions include potential effects on glucose metabolism, possible interactions with insulin signaling, and unknown long-term effects on cellular proliferation
Genetic contextcombined with clinical biomarkers and symptom historycan support a more nuanced treatment discussion
Eskew AM, Wormer KC, Matthews ML, Norton HJ, Papadakis MA, Hurst BS
236 The circadian control of intracellular NAD + levels by the clock is attributed to the oscillation expression of NAMPT, a rate-limiting enzyme in the salvage of NAD + with a 24-hour rhythm
When combined with balanced nutrition and activity, they support fat burning and recovery and may help support overall body composition goals when used alongside your prescribed GLP-1 therapy