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Metabolomic studies have further revealed that serum levels of sphingomyelin (SM) and its hydroxylated form (SM [OH]) are significantly reduced in COPD patients, with SM C24:1 levels exhibiting a negative correlation with glucose clearance
doi:10.1016/j.amjms.2025.07.006 Alharbi SH, et al
the body doesnt always respond on a predictable weekly schedule
However, alternative forms such as liposomal glutathione show promise, as they may enhance bioavailability