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Dhillon added, The second key finding of this animal study is that Skye's highly-peripherally restricted nimacimab drives efficacy similar to a less-peripherally restricted CB1 inhibitor, monlunabant, in a DIO model

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We also found that JWU-A021 failed to stimulate an increase of the [Ca 2+ ] i when the extracellular [Ca 2+ ] was lowered from 2.6 mM to 100 nM (Fig