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"GLP-1 medications are particularly challenging to deliver through the skin

Additionally, underlying health conditions, such as nerve damage, kidney disease, and endocrine disorders, can contribute to dry mouth in diabetics

High-intensity exercise within 2 to 4 hours of injection can worsen nausea, as both exercise and the medication reduce blood flow to the GI tract

Your body absorbs the medication just as well whether you inject it into your abdomen, thigh, or upper armso, all three injection sites are equally effective

The main disadvantage is that evening hunger or cravings before bedtime may feel less suppressed compared to morning dosing