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All samples were then processed again using data-independent acquisition, in this case using 20 ppm and 15 ppm for precursor and fragment ion tolerance, respectively, against the prefabricated spectral library of 69,797 precursors to maximize discovery, precision, and reproducibility of the proteomic spectrum

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Publicly funded research agencies like the National Institutes of Health could play an important role by rapidly investigating the most promising uses of GLP-1 drugs, particularly in areas where pharmaceutical companies may be reluctant to invest, such as traumatic brain injury, for which trials are difficult to run