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In healthy individuals, GLP-1 is released after food consumption, particularly in response to proteins and fats, signaling satiety and stimulating insulin secretion

M., Andersen, S

This suggests that GLP-1 RAs may be most appropriate for adolescents with established obesity who have not responded to comprehensive lifestyle interventions

Here to teach us once more is Carley Moses, who I really REALLY hope you remember from her previous posts on chronic care management and adult vaccinations

For eligible and willing patients, bariatric surgery, which provides sustained benefits, may be the best option from a clinical and economic perspective