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Therefore, ideal cell-free hydrogel scaffolds for cartilage repair should feature the following advantages: the capability for minimally invasive surgery, adequate tissue adhesiveness for local fixation, similar mechanical strength to cartilage tissue, stem cell recruitment, and chondrocyte differentiation

DHA@MIL-101 NRs self-disassembled in the acid microenvironment to dissociate Fe 3+ , achieving GSH consumption-mediated redox reaction and Fe 2+ -mediated Fenton reaction (Figure 5D)

CH functionality is adaptable, enabling improvements to its unique features ( 2 group influences CH immersion in acidic conditions, with a pK a value of 6.5, reportedly demonstrated (Chattopadhyay and Inamdar, 2010)

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