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Understanding these pathways helps explain why the peptide shows such broad therapeutic potential across different tissue types

In addition, GSTs are also involved in conferring multidrug resistance with a non-catalytic mechanism through their inhibition of the JNK signaling pathway, an event that protects tumoral cells from apoptosis, as it will be detailed later

This intrinsic capability suggests considerable potential for leveraging EVs to deliver vitamin D or its bioactive derivatives specifically to neural targets, offering a novel strategy to mitigate cognitive decline [139]

302,303 CD73 also functions as an adhesion molecule that mediates cancer cell migration and invasion