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Neurodegenerative Diseases Hyperuriceamia displays an important causative effect in multiple diseases including gout, CKD, cardiovascular diseases

This process can disrupt membrane integrity, leading to impaired cellular function and cell death.Low Antioxidant Defense: Compared to other tissues, the brain has a relatively modest antioxidant defense system

Neurology 66 , S24S36 (2006)

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