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B12 is the cofactor for methionine synthase (the MTR enzyme), which recycles homocysteine and supports methylation

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doi: 10.1016/j.foodres.2022.111471, 19

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PubMed Systematic reviewGLP-1 class evidence2025 Efficacy of GLP-1 Receptor Agonists on Weight Loss, BMI, and Waist Circumference A broad meta-analysis anchor for GLP-1 weight-loss effect and class-level comparisons

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