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In: Bergmeyen, H.V., Ed., Methods of Enzymatic Analysis, 3rd Edition, Verlog Chemie, Deerfiled Beach
Modulation of Nitric Oxide Nitric oxide (NO) plays a central role in vascular function and tissue repair
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Also, glutamate excitotoxicity NMDA-mediated intra-neuronal calcium overload elevates NO synthesis contributing to oxidative stress particularly the production of reactive nitrogen species which are able to cause defects in DNA and protein phosphorylation pathway (85)
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