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GLP-1 also slows down digestion and makes people feel full after eating

In a phase 3 clinical trial involving 800 participants and lasting 72 weeks, a weekly dose of semaglutide was effective in almost two-thirds of patients at treating a serious form of fatty liver disease known as Metabolic Dysfunction-Associated Steatohepatitis (MASH)

Theyre sometimes used when a patient cant tolerate an ingredient in a generic or branded drug, and are often cheaper to purchase and not subject to ingredient shortages that can make drugs harder or more expensive to make

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for instance, oral doses up to 600 mg daily have been used for several weeks in pregnant women (such as those with gestational diabetes) without evident harm