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Iron is essential for oxygen transport via hemoglobin

Chemistry (2016) 22(46):164415

But in Type 1 diabetes: They do not replace insulin They may promote ketogenesis Insulin dose reductions can trigger euglycemic DKA Appetite suppression and GI effects may worsen metabolic instability Type 1 diabetes management requires maintaining enough insulin not only for glucose control, but also to suppress ketone production

But B12 takes the form of methylcobalamin only after it receives its methyl group from methylfolate, which again, MTHFR is responsible for producing

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