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Failure of Lifestyle Monotherapy Lifestyle modification (LSM) is foundational but often insufficient for long-term weight maintenance in Class II or III obesity: Timing: Patients with a history of weight cycling (yo-yo dieting) are unlikely to achieve sustained success through behavioral interventions alone

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3.4.1 Onset Neuropsychological symptoms are typically more subtle than some of the more severe physical manifestations that are experienced by individuals with FAOD

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Neuropediatrics 2008;39:172-5