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Status: Moving into Phase 3 trials

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Current Availability and Regulatory Status in the UK Retatrutide is not approved by the MHRA and cannot be legally prescribed in the UK outside authorised clinical trials

On the 12mg maintenance dose, participants lost an average of 28.7% of body weight versus 2.1% on placebo, as reported by Eli Lilly in December 2025 (peer-reviewed publication pending)

When that happens, people may experience: Nausea Vomiting Feeling full after only a few bites Bloating Stomach pain or discomfort Heartburn Loss of appetite Feeling overly full long after eating Depending on the cause of stomach paralysis, it can be a temporary issue