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SSRI's do it with serotonin (See CBD and serotonin) Benzos do it with GABA (see CBD and GABA) Nicotine and acetylcholine THC and anandamide It's why ketamine is showing promise for peripheral nerve pain which can result from too much glutamate

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via inhibition of the MYCN transcriptional machinery, synthetic lethality, and destabilization of the MYCN protein (6, 7)

Off-label, it has become the GHRH analog of choice for patients whose primary goal is visceral fat reduction and metabolic improvement

Brain cells are particularly susceptible, owing to their low antioxidant defences and high oxidative metabolic activity