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Total RNA was isolated using TRIzol Reagent (Invitrogen, Breda, The Netherlands)

All these side effects can be seen with oral or transdermal methimazole or oral carbimazole, but GI side effects are typically less common (less than 5%) with transdermal application 10

To overcome a plateau, reassess calorie intake, increase activity, prioritise protein, and consider a doctor-led review of your health and hormone levels

Choosing between them depends on specific health goals, particularly regarding cognitive function and brain health, where ALC may offer additional benefits

People who already experience acid reflux or other upper GI symptoms should approach cautiously