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Rapamycin is another promising autophagy inducer being evaluated in phase 2 trials (Cummings et al., 2023a,b, 2024)

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However, there were no significance differences between ASD children and HC children for the other 17 potential markers

The only clinical study that was performed to determine the resveratrol hepatoprotective effect demonstrated that a 500 mg resveratrol dose administrated for 12 weeks caused a significant reduction in inflammatory cytokines, serum cytokeratin-18, NF-kB activation, liver alanine aminotransferase (ALT), and hepatic steatosis when compared to the placebo group in patients with nonalcoholic fatty liver disease (NAFLD) [46]