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The virus is then uncoating to free its genomic RNA, and the HCV genomic RNA is used both for polyprotein translation and replication in the cytoplasm

Given the procedure may benefit a subset of patients, low-pressure, short-duration hydrodistension is designated as an Option

Overall, the outcome is good, although it is quite unpredictable, with about 30% of patients have a recurrence

Distinguishing injection-site itch from systemic pruritus helps guide whether dose timing, injection site rotation, or systemic management is appropriate

Another study showed similar patterns, with patients losing 5.9% at 3 months and 10.9% at 6 months