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Pending FDA Approval for Chronic Weight Management: As of 2023, Eli Lilly and Company, the manufacturer of Mounjaro, has submitted a supplemental New Drug Application (sNDA) to the FDA seeking approval for Mounjaro as a treatment for chronic weight management in adults with obesity or overweight with at least one weight-related comorbid condition [4]

Treatment with PLC inhibitors showed an inhibitory effect on the secretion of pro-inflammatory cytokines, suggesting that PLC signaling in macrophages might regulate the immune response against the mycobacteria (Yadav et al., 2006

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