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They are primarily used for managing type 2 diabetes but are also prescribed for weight loss in some cases

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The pH may be adjusted with a hydrochloric acid solution and/or sodium hydroxide solution

Moreover, the use of analgesic medications, such as opioids, can exacerbate this dysbiosis, damage the intestinal epithelial barrier function and promote the translocation of gut microbiota, which increased susceptibility to PND (Mora et al., 2012

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