Acknowledgements This work was supported by the National Natural Science Foundation of China [grant number 62376256], Research Funds of Centre for Leading Medicine and Advanced Technologies of IHM [grant number 2023IHM01041], Clinical medical research Transformation Project of Anhui Province [Grant Number 202204295107020020], and the Joint Fund for Medical Artificial Intelligence [Grant number MAI2022Q011]
Fast responders may notice reduced morning stiffness or decreased pain during daily activities
MK-801, as an NMDA receptor inhibitor, causes a number of changes in the functioning of neurons, including an increase in glutamate release, which may lead to an increase in excitotoxicity, oxidative stress and, consequently, cell death
A glutathione injection delivers this antioxidant directly into the bloodstream, ensuring faster absorption compared to oral supplements
ST: Writing review & editing