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Rodbard HW, Rosenstock J, Canani LH, Deerochanawong C, Gumprecht J, Lindberg S, et al
See Table 1
Diabetes Nutr Metab 17:336342 Hansotia T, Baggio LL, Delmeire D et al (2004) Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors
This law dates back to 2003, around the time of the fen-phen scandal, when it was found to cause serious heart problems
Degradation of any single domain changes the compound activity profile in ways that compromise research validity
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