Tirzepatide, a dual GIP/GLP-1 receptor agonist, is approved for obesity and type 2 diabetes in adults [93,94]
But the 5mL volume requires more storage space in your refrigerator and increases the surface area exposed to potential contamination each time you draw a dose
In certain instances, once drug exposure (e.g., concentration in the endolymph or perilymph) of a drug reaches steady state, the concentration of the drug in the endolymph or perilymph stays at or about the therapeutic dose for an extended period of time (e.g., one day, 2 days, 3 days, 4 days, 5 days, 6 days, 1 week, 2 weeks, 3 weeks, a month, two months, three months, six months, or one year)
Fluid shifts: GLP-1 drugs can affect body fluid balance, potentially impacting optic nerve perfusion
Pharmacological intervention to restore connectivity deficits of neuronal networks derived from ASD patient iPSC with a TSC2 mutation