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Type 2 Diabetes Focus Tirzepatide Tirzepatide has 5 SURPASS T2D trials, FDA approval for diabetes (Mounjaro), and demonstrated superiority over semaglutide in SURPASS-2
( H ) Intracellular cAMP accumulation in human caSMCs treated with the sAC inhibitor KH7 (25 M, dark gray bars), the tmAC inhibitor Ddox (50 M, white bars), or PBS (light gray bars) for 3 hours followed by a 15-minute treatment with GLP-1(2836), scrambled control, IPE, or forskolin
Cellular fatty acid uptake is facilitated by a family of 6 evolutionarily conserved plasma membrane fatty acid transport proteins (FATP16), which are expressed in a tissue-specific fashion (4)
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DOI.org (Crossref), Najjar, Rami S., et al
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