80.1 Fujii A, Yoneda M, Ito T, Yamamura O, Satomi S, Higa H, Kimura A, Suzuki M, Yamashita M, Yuasa T, Suzuki H, Kuriyama M
But your body will try to protect you from disease or any other health issues by producing antioxidants
It also suppressed NF-B p65 and p38 MAPK signaling pathways and protected the lungs by reducing reactive oxygen species (ROS) production, stimulating superoxide dismutase (SOD), while decreasing TNF- and IL-6 production [ 46 ]
Consequently, its activity reflects the cells energy state and redox balance and can modulate mitochondrial ROS production under conditions of high NADH/NAD + ratios or impaired electron flow
During hypoxia-reperfusion cycles, ROS production increases, overwhelming the antioxidant defense system and promoting ferroptosis in trophoblast cells (Figure 1