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Long-term depletion is now being linked with Alzheimers disease

the latter serves as an energy reservoir, provides effective thermal insulation in cold environments, protects internal organs through mechanical cushioning, and connects to muscles and other supporting structures [29, 30]

Brittle cornea syndrome is characterized by thin corneaa, early-onset progressive keratoglobus (cornea becomes extremely thin and change to a more globular shape than its normal gradual curve.) or keratoconus (begins to bulge into a cone-like shape), and blue sclerae (the white of the eye) Classic symptoms, such as hypermobile joints and hyperelastic skin, are also seen often

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