Specifically, we looked into the following areas: Effectiveness Cost Safety Convenience Lets take a look at each criterion in a little more detail
One advantage of noncompetitive and uncompetitive inhibitors over competitive inhibitors in disruption of metabolic pathways, is the lack of competition with endogenous substrates that may be present at high cellular concentrations as a result of enzyme inhibition, making uncompetitive inhibitors, in particular, ideal for drug development 58
Iso H, Moriyama Y, Sato S, et al
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The balance of evidence suggests that the risks of uncontrolled fever outweigh the hypothetical, unproven risks of acetaminophen exposure