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It is entirely possible that the slight rise in optic nerve issues reflects the underlying, advanced vascular damage or high baseline cardiovascular strains already present in patients who require these stronger medications, rather than a direct toxic effect of the drug molecules themselves

These drugs were originally developed to help manage blood sugar in people with Type 2 diabetes, but they have also gained widespread attention for their ability to support weight loss

A shortage of vitamin B12 in the body can lead to severe health problems

In proximal renal tubular epithelial cells (TECs), autophagy inhibition, such as chloroquine or ATG7 depletion, reduces fibrosis, suggesting that autophagy may promote injury (Nam et al., 2019)

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