Engelbrecht Y, de Wet H, Horsch K, Langeveldt CR, Hough FS, Hulley PA
Avoid any provider unwilling to document these assessments thoroughly
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Wegovy and Zepbound are specifically approved for weight management, which simplifies this particular issue, but doesn't eliminate the other hurdles
Notably, the observed reductions in the odds of substance use disorders, including a 74% decrease in the odds of AUD, a 69% reduction for OUD, a 68% reduction for NUD, and a 75% reduction for CUD, among GLP-1 RA users were consistent with emerging preclinical and clinical studies showing that GLP-1 RA modulates reward pathways in the brain to reduce SUD (32)