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Research documented that 24-month-old mice (equivalent to approximately 70 human years) treated with FOXO4-DRI showed significant improvements in wheel running activity, suggesting restoration of physical capacity and vitality through senescent cell elimination

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This has sparked interest in innovative therapeutic approaches, especially those utilizing mesenchymal stem cell-derived exosomes (MSC-Exos), which are known for their natural biocompatibility and diverse cytoprotective effects [7]