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18 found that P53 inhibits erastin-induced ferroptosis in CRC cells by blocking the activity of dipeptidyl-peptidase-4 (DPP4), which was different from the previous role of P53 in promoting ferroptosis in other cancer cells

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LD50 has not been established because researchers could not achieve lethal doses in standard protocols 1

Considerations include the type of surgery you had (gastric bypass, sleeve gastrectomy, etc.), how the altered anatomy might affect medication absorption and tolerability, your current weight and whether additional weight loss is medically appropriate, and any nutritional deficiencies or complications from surgery