Pemvidutide Pemvidutide, another weekly GLP-1/glucagon dual agonist, is under evaluation in the ongoing phase 2 IMPACT trial (NCT05989711) in 190 individuals with histologically confirmed MASH and fibrosis stages F2-F3 [47]
Women with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN2) should discuss their individual risk with a specialist before using any agent in this class, as the clinical significance in humans remains uncertain
Any product claiming to be an over-the-counter GLP-1 agonist medication is either lying, unsafe, or both
Cardiomyocyte/cardiac fibroblast dysfunction is related to abnormal proliferation, apoptosis, hypertrophy, as well as inflammation and fibrosis, which may be caused by mitochondrial dysfunction and metabolic disorders
Judicial Panel on Multidistrict Litigation