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Clinical Evidence on Semaglutide and Birth Control Safety Major clinical trials for semaglutide, including the SUSTAIN and SELECT trials, did not report contraceptive failure as a primary concern

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This does not make all semaglutide products automatically interchangeable

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Given the beneficial metabolic and cardiovascular actions of semaglutide, and the low risk for severe adverse events, semaglutide has an overall favorable risk/benefit profile for patient with type 2 diabetes