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Semaglutide has a very hydrophobic component in its structure, meaning its not easily dissolved in water and thus challenging to manufacture. The team used a chemical process called glycosylation, which differs to the lipidation process used to make semaglutide, to make an analogue of GLP-1 that is hydrophilic and much more easily dissolved

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Pain that only occurs when youre in a certain position may indicate an issue other than a heart attack