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Stem Cells 35 (12), 23232330

Tirzepatide frequently causes nausea, vomiting, diarrhea, and decreased appetite, particularly during dose initiation and escalation

& Fujii, J

Another systematic review [80] examined the effect of GLP-1RAs on psychiatric symptoms, with studies classifying primary or secondary psychiatric outcomes

Increased GH and IGF-1 may indirectly modulate gonadotropins and sex steroids to support ovulation and spermatogenesis, so track LH, FSH, testosterone, estrogen, progesterone, and SHBG to assess response