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Among specific GLP-1Ra agents, tirzepatide showed the strongest association with reduced mortality (HR = 0.16), followed by semaglutide (HR = 0.27) and dulaglutide (HR = 0.52)

Being obese is also another risk factor as the additional weight subjects the spine and vertebrae to more stress and pressure

or spontaneous oxidation of free GSH to GSSG) if plasma is not analyzed on the same day as collection

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