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As carnitine reduces the intracellular concentration of typical markers of cell sufferance and/or apoptosis, our data strongly suggest that the drug exerts a negative control on the progression of apoptotic death at retinal cell level

The study is reported in accordance with the ARRIVE guidelines

Dichotomous outcomes were analyzed using RR and 95% CI calculated from fixed-effects models

However, development of a small molecule capable of stimulating HGF, and its associated receptor c-Met, may be clinically efficacious

So, by ensuring the safe and effective administration of the correct dosage, PT-141 can offer optimal therapeutic gains to people