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Ascha et al., 2016

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The increase in active GLP-1 levels helps to improve glycemic control and insulin secretion ( + ), M1 macrophages (CD14 + CD80 + ), and M2 macrophages (CD14 + CD206+), as well as the differences in surface GLP-1 receptor (GLP-1R) expression in peripheral blood between coronary heart disease patients and healthy control individuals, and found that GLP-1 promotes M2 macrophage polarization and alleviates atherosclerosis through its interaction with the GLP-1R (Yang L