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Treatment with an anti-CD226 monoclonal antibody reduced proliferation of CD4+ T cells and of CD8+ effector memory T cells in the spleen of female NOD mice, as well as the frequencies of autoreactive CD8+ T cells in the pancreas (96)

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It also supports the deiodinase enzymes involved in converting T4 to active T3, a key step in thyroid hormone metabolism, and contributes to normal immune cell function as part of a balanced diet

The platform employed an iterative geometric placement optimization algorithm to minimize overlaps between the upper and lower leaflets, ultimately generating the most stable spherical liposome model